GrippeEspagneV1, Main, Exploration, bibRecord, 000084

[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

Identifieur interne : 000084 ( Main/Exploration ); précédent : 000083; suivant : 000085

[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

Auteurs : Naiara Ortiz-Lana [Espagne] ; Elisa Garrote [Espagne] ; Javier Arístegui [Espagne] ; Joseba Rementeria [Espagne] ; Juan-Antonio García-Martínez [Espagne] ; Cynthia Mccoig [Espagne] ; Pilar García-Corbeira [Espagne] ; Raghavendra Devadiga [Inde] ; M Nica Tafalla

Source :

Anales de pediatria (Barcelona, Spain : 2003) [ 1695-9531 ] ; 2017.

RBID : pubmed:28363360

Descripteurs français

KwdFr :
- Adolescent (MeSH), Coûts indirects de la maladie (MeSH), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Espagne (épidémiologie), Facteurs temps (MeSH), Femelle (MeSH), Grippe humaine (épidémiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Mâle (MeSH), Nourrisson (MeSH), Nouveau-né (MeSH), Service hospitalier d'urgences (MeSH), Études prospectives (MeSH).
MESH :
- statistiques et données numériques : Hospitalisation.
- épidémiologie : Espagne, Grippe humaine.
- Adolescent, Coûts indirects de la maladie, Enfant, Enfant d'âge préscolaire, Facteurs temps, Femelle, Humains, Mâle, Nourrisson, Nouveau-né, Service hospitalier d'urgences, Études prospectives.
Wicri :
- geographic : Espagne.

English descriptors

KwdEn :
- Adolescent (MeSH), Child (MeSH), Child, Preschool (MeSH), Cost of Illness (MeSH), Emergency Service, Hospital (MeSH), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Infant (MeSH), Infant, Newborn (MeSH), Influenza, Human (epidemiology), Male (MeSH), Prospective Studies (MeSH), Spain (epidemiology), Time Factors (MeSH).
MESH :
- geographic , epidemiology : Spain.
- epidemiology : Influenza, Human.
- statistics & numerical data : Hospitalization.
- Adolescent, Child, Child, Preschool, Cost of Illness, Emergency Service, Hospital, Female, Humans, Infant, Infant, Newborn, Male, Prospective Studies, Time Factors.

Abstract

INTRODUCTION

This study was undertaken to estimate the burden of morbidity associated with laboratory-confirmed influenza in children below 15 years of age.

PATIENTS AND METHODS

Children presenting with acute respiratory infection and/or isolated fever at the Basurto University Hospital, Bilbao, Spain between November 2010 and May 2011 were included in this study (NCT01592799). Two nasopharyngeal secretion samples were taken from each; one for a rapid influenza diagnostic test in the emergency department, and the second for laboratory analysis using real-time polymerase chain reaction and viral culture.

RESULTS

A total of 501 children were recruited, of whom 91 were hospitalized. Influenza diagnosis was confirmed in 131 children (26.1%); 120 of 410 (29.3%) treated as outpatients and 11 of 91 (12.1%) hospitalized children. A total of 370 of 501 children (73.9%) had no laboratory test positive for influenza. The proportion of subjects with other respiratory viruses was 145/501 (28.9%) cases and co-infection with the influenza virus plus another respiratory virus was detected in 7/501 (1.4%) cases. Influenza virus types were: A (H1N1 and H3N2) 53.2% (67/126); B (Victoria and Yamagata) 46.0% (58/126); A+B 0.8% (1/126). The median direct medical costs associated with each case of laboratory-confirmed influenza was €177.00 (N=131). No significant differences were observed between the medical costs associated with influenza A and B.

CONCLUSION

Almost half of the cases were influenza virus B type. The administration of a vaccine containing influenza A and B types to children below 15 years of age might reduce the overall burden of the illness.

DOI: 10.1016/j.anpedi.2016.10.016
PubMed: 28363360
PubMed Central: PMC7105034

Affiliations:

Espagne, Inde

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 00096
to stream Main, to step Curation: 000096

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Cost of Illness (MeSH)</term>
<term>Emergency Service, Hospital (MeSH)</term>
<term>Female (MeSH)</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Infant, Newborn (MeSH)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Male (MeSH)</term>
<term>Prospective Studies (MeSH)</term>
<term>Spain (epidemiology)</term>
<term>Time Factors (MeSH)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Coûts indirects de la maladie (MeSH)</term>
<term>Enfant (MeSH)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Facteurs temps (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Nouveau-né (MeSH)</term>
<term>Service hospitalier d'urgences (MeSH)</term>
<term>Études prospectives (MeSH)</term>
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</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Cost of Illness</term>
<term>Emergency Service, Hospital</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
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<term>Prospective Studies</term>
<term>Time Factors</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Coûts indirects de la maladie</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
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<front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b>
</p>
<p>This study was undertaken to estimate the burden of morbidity associated with laboratory-confirmed influenza in children below 15 years of age.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>PATIENTS AND METHODS</b>
</p>
<p>Children presenting with acute respiratory infection and/or isolated fever at the Basurto University Hospital, Bilbao, Spain between November 2010 and May 2011 were included in this study (NCT01592799). Two nasopharyngeal secretion samples were taken from each; one for a rapid influenza diagnostic test in the emergency department, and the second for laboratory analysis using real-time polymerase chain reaction and viral culture.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A total of 501 children were recruited, of whom 91 were hospitalized. Influenza diagnosis was confirmed in 131 children (26.1%); 120 of 410 (29.3%) treated as outpatients and 11 of 91 (12.1%) hospitalized children. A total of 370 of 501 children (73.9%) had no laboratory test positive for influenza. The proportion of subjects with other respiratory viruses was 145/501 (28.9%) cases and co-infection with the influenza virus plus another respiratory virus was detected in 7/501 (1.4%) cases. Influenza virus types were: A (H1N1 and H3N2) 53.2% (67/126); B (Victoria and Yamagata) 46.0% (58/126); A+B 0.8% (1/126). The median direct medical costs associated with each case of laboratory-confirmed influenza was €177.00 (N=131). No significant differences were observed between the medical costs associated with influenza A and B.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>Almost half of the cases were influenza virus B type. The administration of a vaccine containing influenza A and B types to children below 15 years of age might reduce the overall burden of the illness.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28363360</PMID>
<DateCompleted><Year>2019</Year>
<Month>01</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>06</Month>
<Day>05</Day>
</DateRevised>
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<JournalIssue CitedMedium="Internet"><Volume>87</Volume>
<Issue>6</Issue>
<PubDate><Year>2017</Year>
<Month>Dec</Month>
</PubDate>
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<Title>Anales de pediatria (Barcelona, Spain : 2003)</Title>
<ISOAbbreviation>An Pediatr (Barc)</ISOAbbreviation>
</Journal>
<ArticleTitle>[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].</ArticleTitle>
<Pagination><MedlinePgn>311-319</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.anpedi.2016.10.016</ELocationID>
<Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">This study was undertaken to estimate the burden of morbidity associated with laboratory-confirmed influenza in children below 15 years of age.</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Children presenting with acute respiratory infection and/or isolated fever at the Basurto University Hospital, Bilbao, Spain between November 2010 and May 2011 were included in this study (NCT01592799). Two nasopharyngeal secretion samples were taken from each; one for a rapid influenza diagnostic test in the emergency department, and the second for laboratory analysis using real-time polymerase chain reaction and viral culture.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 501 children were recruited, of whom 91 were hospitalized. Influenza diagnosis was confirmed in 131 children (26.1%); 120 of 410 (29.3%) treated as outpatients and 11 of 91 (12.1%) hospitalized children. A total of 370 of 501 children (73.9%) had no laboratory test positive for influenza. The proportion of subjects with other respiratory viruses was 145/501 (28.9%) cases and co-infection with the influenza virus plus another respiratory virus was detected in 7/501 (1.4%) cases. Influenza virus types were: A (H1N1 and H3N2) 53.2% (67/126); B (Victoria and Yamagata) 46.0% (58/126); A+B 0.8% (1/126). The median direct medical costs associated with each case of laboratory-confirmed influenza was €177.00 (N=131). No significant differences were observed between the medical costs associated with influenza A and B.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Almost half of the cases were influenza virus B type. The administration of a vaccine containing influenza A and B types to children below 15 years of age might reduce the overall burden of the illness.</AbstractText>
<CopyrightInformation>Copyright © 2016 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ortiz-Lana</LastName>
<ForeName>Naiara</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Garrote</LastName>
<ForeName>Elisa</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España. Electronic address: mariaisabel.garrotellanos@osakidetza.net.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Arístegui</LastName>
<ForeName>Javier</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Rementeria</LastName>
<ForeName>Joseba</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>García-Martínez</LastName>
<ForeName>Juan-Antonio</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Departamento Médico, GSK, Tres Cantos (Madrid), España.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Cynthia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Departamento Médico, GSK, Tres Cantos (Madrid), España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>García-Corbeira</LastName>
<ForeName>Pilar</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Departamento Médico, GSK, Tres Cantos (Madrid), España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Devadiga</LastName>
<ForeName>Raghavendra</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>CDOC-B, GSK, Bangalore, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tafalla</LastName>
<ForeName>Mónica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>GSK, Wavre, Bélgica.</Affiliation>
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<Language>spa</Language>
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<VernacularTitle>Estudio prospectivo para estimar la carga de hospitalización y visitas a urgencias de la gripe en población pediátrica en Bilbao (2010-2011).</VernacularTitle>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>03</Month>
<Day>28</Day>
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<MedlineJournalInfo><Country>Spain</Country>
<MedlineTA>An Pediatr (Barc)</MedlineTA>
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<MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
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</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Emergency department</Keyword>
<Keyword MajorTopicYN="Y">España</Keyword>
<Keyword MajorTopicYN="Y">Gripe</Keyword>
<Keyword MajorTopicYN="Y">Hospitalización</Keyword>
<Keyword MajorTopicYN="Y">Hospitalization</Keyword>
<Keyword MajorTopicYN="Y">Influenza</Keyword>
<Keyword MajorTopicYN="Y">Servicio de Urgencia</Keyword>
<Keyword MajorTopicYN="Y">Spain</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>04</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2016</Year>
<Month>10</Month>
<Day>13</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>10</Month>
<Day>14</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>4</Month>
<Day>2</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>1</Month>
<Day>5</Day>
<Hour>6</Hour>
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<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
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<Hour>6</Hour>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28363360</ArticleId>
<ArticleId IdType="pii">S1695-4033(16)30338-1</ArticleId>
<ArticleId IdType="doi">10.1016/j.anpedi.2016.10.016</ArticleId>
<ArticleId IdType="pmc">PMC7105034</ArticleId>
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</PubmedData>
</pubmed>
<affiliations><list><country><li>Espagne</li>
<li>Inde</li>
</country>
</list>
<tree><noCountry><name sortKey="Tafalla, M Nica" sort="Tafalla, M Nica" uniqKey="Tafalla M" first="M Nica" last="Tafalla">M Nica Tafalla</name>
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<country name="Espagne"><noRegion><name sortKey="Ortiz Lana, Naiara" sort="Ortiz Lana, Naiara" uniqKey="Ortiz Lana N" first="Naiara" last="Ortiz-Lana">Naiara Ortiz-Lana</name>
</noRegion>
<name sortKey="Aristegui, Javier" sort="Aristegui, Javier" uniqKey="Aristegui J" first="Javier" last="Arístegui">Javier Arístegui</name>
<name sortKey="Garcia Corbeira, Pilar" sort="Garcia Corbeira, Pilar" uniqKey="Garcia Corbeira P" first="Pilar" last="García-Corbeira">Pilar García-Corbeira</name>
<name sortKey="Garcia Martinez, Juan Antonio" sort="Garcia Martinez, Juan Antonio" uniqKey="Garcia Martinez J" first="Juan-Antonio" last="García-Martínez">Juan-Antonio García-Martínez</name>
<name sortKey="Garrote, Elisa" sort="Garrote, Elisa" uniqKey="Garrote E" first="Elisa" last="Garrote">Elisa Garrote</name>
<name sortKey="Mccoig, Cynthia" sort="Mccoig, Cynthia" uniqKey="Mccoig C" first="Cynthia" last="Mccoig">Cynthia Mccoig</name>
<name sortKey="Rementeria, Joseba" sort="Rementeria, Joseba" uniqKey="Rementeria J" first="Joseba" last="Rementeria">Joseba Rementeria</name>
</country>
<country name="Inde"><noRegion><name sortKey="Devadiga, Raghavendra" sort="Devadiga, Raghavendra" uniqKey="Devadiga R" first="Raghavendra" last="Devadiga">Raghavendra Devadiga</name>
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[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

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